Name | 9-fluorenone-4-carboxylic acid |
Synonyms | Einecs 228-311-9 RARECHEM AL BO 1176 9-Fluorenone-4-carbo 9-FLUORENONE-4-CARBOXYLIC ACID 9-fluorenone-4-carboxylic acid 9-OXOFLUORENE-4-CARBOXYLIC ACID 9-Oxofluorene-4-carboxylic acid 9-oxo-9H-fluorene-4-carboxylate 9-OXO-4-FLUORENECARBOXYLIC ACID 9-OXO-9H-FLUORENE-4-CARBOXYLIC ACID 9-oxo-9H-fluorene-4-carboxylic acid 9-Oxofluorene-4-carboxylic acid,9-Fluorenone-4-carboxylic acid |
CAS | 6223-83-2 |
EINECS | 228-311-9 |
InChI | InChI=1/C14H8O3/c15-13-9-5-2-1-4-8(9)12-10(13)6-3-7-11(12)14(16)17/h1-7H,(H,16,17)/p-1 |
InChIKey | AFQYQSWTVCNJQT-UHFFFAOYSA-N |
Molecular Formula | C14H8O3 |
Molar Mass | 224.21 |
Density | 1.424±0.06 g/cm3(Predicted) |
Melting Point | 225-227°C(lit.) |
Boling Point | 476.5±24.0 °C(Predicted) |
Flash Point | 256.1°C |
Vapor Presure | 6.9E-10mmHg at 25°C |
Appearance | powder to crystal |
Color | Light orange to Yellow to Green |
BRN | 2694801 |
pKa | 3.46±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
MDL | MFCD00001145 |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
Hazard Class | IRRITANT |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
Application | 9-fluorenone-4-carboxylic acid can be used as a pharmaceutical synthesis intermediate, and can be used as a reaction raw material from dibenzoic acid, under the action of concentrated sulfuric acid, the cyclization reaction takes place. |
preparation | dibenzoic acid (40.0g,165mmol) and H2SO4(96%;d = 1.84 gmL-1;80ml) heated and stirred at 110-115°C for 30 min. After dissolving the dibenzoic acid in 5-10 min, a dark red solution is obtained, the mixture is cooled to room temperature and poured into ice water (400ml), the yellow precipitate is filtered off, washing well with water until pH = 7, drying to give the product 9-fluorenone-4-carboxylic acid, yield (36.85g,99.5%) the product is sufficiently pure; Recrystallization from acetic acid (), yield:(33.05g,89.3%) as yellow needles. |